Seriously and occasionally, hypersensitivity (anaphylactic) reactions have been reported in patients receiving β-lactam therapy. These reactions are more apt to occur in individuals with history of hypersensitivity reactions to multiple allergens. If any allergic reaction occurs, the drug should be discontinued and the appropriate therapy instituted. Serious anaphylactic reactions require immediate emergency treatment with epinephrine, oxygen, IV steroids and airway management, including intubation, should be administered as indicated.